Depression is a treatable condition, but for some people, standard treatments aren’t effective. Repetitive TMS is typically used when standard treatments such as medications and talk therapy (psychotherapy) don’t work.
In 2008, rTMS was approved for use by the FDA as a treatment for major depression for patients who do not respond to at least one antidepressant medication in the current episode.
The first clinical trial for TMS funded by NIMH, was published in 2010 found that 14% achieved remission with rTMS compared to 5% with an inactive (sham) treatment. After the trial ended, patients could enter a second phase in which everyone, including those who previously received the sham treatment, was given rTMS. Remission rates during the second phase climbed to nearly 30%.
Clinical studies with over 900 people have shown that TMS may help achieve remission for people living with depression.
TMS was included in the 2010 American Psychiatric Association (APA) Practice Guideline for the Treatment of Patients with Major Depression—guidelines that provide recommendations for how psychiatrists treat depression.
Every day with depression is a struggle. When antidepressant medications aren’t working, it’s hard to know what to turn to next.
Many people with Major Depressive Disorder have turned to TMS Therapy to take control of their depression. Hear their stories: